We've refreshed the visualizations for variant effect predictions (DeepSEA or ExPecto), improving the performance for large sequence submissions (1000+ variants) and visualization of chromosome positions.
ExPecto makes highly accurate cell-type-specific predictions of gene expression solely from DNA sequence (details here). Researchers can now run ExPecto on their variants of interest, along with exploring our pre-computed ExPecto predictions. HumanBase will automatically identify the gene whose TSS is closest to a submitted variant and predict the impact of that variant on the gene's expression in 200+ tissues and cell-types.
By Susan Reslewic Keatley
This powerful, dynamic software system is changing how scientists sift through the recent deluge of human genomic data — and deepening our knowledge of human biology, health and disease. Read more