What's New in HumanBase


August 2025

Updated Downloads Section:

We have redesigned the Downloads page to provide better organization and access to HumanBase resources. The page now includes new bulk download zip files for all top edges, full networks, and gold standards, as well as a Python script for downloading all tissue-specific networks incrementally with error handling. It also features downloadable resources for HumanBase variant prediction tools.

Enhanced Downloads page showing Variant Effects tab with organized resources

Use Cases:

We have added an extensive collection of use cases/tutorials to the interface demonstrating real research workflows for variant effect prediction and network analysis frameworks.

Enhanced Score Documentation:

We have expanded documentation of score types reported by HumanBase variant effect prediction frameworks and provided tooltip links to relevant score documentation sections from the interface.

Score dropdowns with direct documentation links

October 2024

Expanded Enrichment Databases:

We have enhanced the Functional Module Detection tool by adding support for multiple databases. Previously, only Gene Ontology Biological Process (GO BP) terms were available. Now, you can explore enrichment analysis of the detected modules from the following four databases:

Functional Enrichment with multiple databases

July 2024

Interactive API Documentation:

We added interactivity to all endpoints with working examples in the API documentation. This allows users to experiment with the API directly from the documentation page.

Check out the new API documentation here.


Functional Module Detection:

Functional Module Detection results may now be optionally named with a title.

Functional Module Detection query with title input field

The title will show in the browser as well as in the file name of the download files. There is a new breadcrumb navigation across all of HumanBase for better context while browsing the site.

Functional Module Detection browser shows the result title